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Anti-CD68 Antibody-FITC (9Z25)
还可以产品编号 TMAY-01736F
Anti-CD68 Antibody-FITC (9Z25) 是一种 FITC-conjugated Mouse 抗体，靶向 CD68。Anti-CD68 Antibody-FITC (9Z25) 可用于 FCM。
Anti-CD68 Antibody-FITC (9Z25)
Anti-CD68 Antibody-FITC (9Z25)
还可以产品编号 TMAY-01736F
Anti-CD68 Antibody-FITC (9Z25) 是一种 FITC-conjugated Mouse 抗体，靶向 CD68。Anti-CD68 Antibody-FITC (9Z25) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-CD68 Antibody-FITC (9Z25) is a FITC-conjugated Mouse antibody targeting CD68. Anti-CD68 Antibody-FITC (9Z25) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9Z25 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of human CD68 expression on human whole blood monocytes.The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with FITC-conjugated anti-Human CD68. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD68 (rh CD68; TMPY-02972; P34810-1; Met1-Ser319). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography, and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Macrosialin, also known as CD68 and Gp11, is a single-pass type I membrane protein which belongs to theLAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human CD68 Protein (TMPY-02972) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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