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Anti-HIF-2 alpha Antibody (2T387)

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货号 TMAB-07033

Anti-HIF-2 alpha Antibody (2T387) 是一种 Rabbit 抗体，靶向 HIF-2 alpha。Anti-HIF-2 alpha Antibody (2T387) 可用于 WB,ICC/IF,FCM。

Anti-HIF-2 alpha Antibody (2T387)

Anti-HIF-2 alpha Antibody (2T387)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07033

Anti-HIF-2 alpha Antibody (2T387) 是一种 Rabbit 抗体，靶向 HIF-2 alpha。Anti-HIF-2 alpha Antibody (2T387) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-HIF-2 alpha Antibody (2T387) is a Rabbit antibody targeting HIF-2 alpha. Anti-HIF-2 alpha Antibody (2T387) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
2T387
反应种属
Human,Mouse,Rat
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus (Potential).
组织特异性Expressed in most tissues, with highest levels in lung, followed by heart, kidney, brain and liver. Predominantly expressed in endothelial cells. Also found in smooth muscle cells of the uterus, neurons, and brown adipose tissue. High expression in embryonic choroid plexus and kidney glomeruli.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
抗原信息
免疫原
A synthesized peptide: human HIF 2 alpha
抗原种属
Human
基因名称
EPAS1
基因ID
2034
蛋白名称
Endothelial PAS domain-containing protein 1
Uniprot ID
Q99814
功能
Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
化学信息
分子量Theoretical: 96 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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