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Anti-CBFb Antibody (2U809)

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货号 TMAB-03709

Anti-CBFb Antibody (2U809) 是一种 Rabbit 抗体,靶向 CBFb。Anti-CBFb Antibody (2U809) 可用于 IHC-P,IHC-Fr,IF。

Anti-CBFb Antibody (2U809)

Anti-CBFb Antibody (2U809)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03709

Anti-CBFb Antibody (2U809) 是一种 Rabbit 抗体,靶向 CBFb。Anti-CBFb Antibody (2U809) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-CBFb Antibody (2U809) is a Rabbit antibody targeting CBFb. Anti-CBFb Antibody (2U809) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
2U809
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
抗原信息
免疫原
A synthesized peptide: human CBF beta
抗原种属
Human
基因名称
CBFB
基因ID
蛋白名称
Core-binding factor subunit beta
Uniprot ID
功能
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1.
化学信息
分子量Theoretical: 22 kDa. Actual: 22 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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