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顶部生物活性储存和溶解信息计算器

Anti-Filamin-A Antibody (7B270)

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产品编号 TMAH-00441

Anti-Filamin-A Antibody (7B270) 是一种抗体，靶向 Filamin-A。Anti-Filamin-A Antibody (7B270) 可用于 ELISA,IHC。

Anti-Filamin-A Antibody (7B270)

Anti-Filamin-A Antibody (7B270)

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Rating icon 还可以
产品编号 TMAH-00441

Anti-Filamin-A Antibody (7B270) 是一种抗体，靶向 Filamin-A。Anti-Filamin-A Antibody (7B270) 可用于 ELISA,IHC。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-Filamin-A Antibody (7B270) is an antibody targeting Filamin-A. Anti-Filamin-A Antibody (7B270) can be used in ELISA,IHC.
Ig Type
Rabbit IgG
克隆号
7B270
交叉反应
Human
验证活性
IHC image of TMAH-00441 diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
应用ELISAIHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Perikaryon. Cell projection, growth cone.
组织特异性Ubiquitous.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking. Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance. During the axon guidance process, required for growth cone collapse induced by SEMA3A-mediated stimulation of neurons.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Filamin A
抗原种属
Human
基因名称
FLNA
基因ID
2316
Uniprot ID
P21333
研究领域
Signal transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

α-filaminαfilaminNon-muscle filaminFLN-AFLNAFLN1FLN 1FLNFilamin-AFilamin-1Filamin1Endothelial actin-binding proteinAlpha-filamina-filaminActin-binding protein 280 (ABP-280)ABP-280ABP280

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