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Anti-Filamin-A Antibody (7B270)
还可以产品编号 TMAH-00441
Anti-Filamin-A Antibody (7B270) 是一种抗体，靶向 Filamin-A。Anti-Filamin-A Antibody (7B270) 可用于 ELISA, IHC。
Anti-Filamin-A Antibody (7B270)
Anti-Filamin-A Antibody (7B270)
还可以产品编号 TMAH-00441
Anti-Filamin-A Antibody (7B270) 是一种抗体，靶向 Filamin-A。Anti-Filamin-A Antibody (7B270) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Filamin-A Antibody (7B270) is an antibody targeting Filamin-A. Anti-Filamin-A Antibody (7B270) can be used in ELISA, IHC. |
| Ig Type | Rabbit IgG |
| 克隆号 | 7B270 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00441 diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Perikaryon. Cell projection, growth cone. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking. Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance. During the axon guidance process, required for growth cone collapse induced by SEMA3A-mediated stimulation of neurons. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Filamin A |
| 抗原种属 | Human |
| 基因ID | 2316 |
| Uniprot ID | |
| 研究领域 | Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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