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Anti-S100A1 Antibody (1A890)
还可以产品编号 TMAY-03200
Anti-S100A1 Antibody (1A890) 是一种 Rabbit 抗体，靶向 S100A1。Anti-S100A1 Antibody (1A890) 可用于 IHC-P。
Anti-S100A1 Antibody (1A890)
Anti-S100A1 Antibody (1A890)
还可以产品编号 TMAY-03200
Anti-S100A1 Antibody (1A890) 是一种 Rabbit 抗体，靶向 S100A1。Anti-S100A1 Antibody (1A890) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-S100A1 Antibody (1A890) is a Rabbit antibody targeting S100A1. Anti-S100A1 Antibody (1A890) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1A890 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Immunochemical staining of mouse S100A1 in mouse heart with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human mouse S100A1 in mouse bone with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to chondrocyte. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse S100A1 (rM S100A1; TMPY-02532; P56565; Gly2-Ser94). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse S100A1 protein (TMPY-02532) |
| 抗原种属 | Mouse |
| 研究领域 | Calcium-binding Proteins and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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