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Anti-FBXL18 Polyclonal Antibody

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货号 TMAB-05921

Anti-FBXL18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FBXL18。Anti-FBXL18 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,WB。

Anti-FBXL18 Polyclonal Antibody

Anti-FBXL18 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05921

Anti-FBXL18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FBXL18。Anti-FBXL18 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrICC/IFIFWB
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination. FBL18 directly interacts with SKP1A p19 and CUL-1, forming a substrate-recognition component of the SCF-type E3 ubiquitin ligase complex. Four isoforms of FBL18 exist due to alternative splicing.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FBXL18
抗原种属
Human
基因名称
FBXL18
基因ID
蛋白名称
F-box/LRR-repeat protein 18
Uniprot ID
功能
FBXL18 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
化学信息
分子量Theoretical: 88 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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