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Anti-FBXL18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FBXL18。Anti-FBXL18 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,WB。
Anti-FBXL18 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FBXL18。Anti-FBXL18 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrICC/IFIFWB |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | FBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination. FBL18 directly interacts with SKP1A p19 and CUL-1, forming a substrate-recognition component of the SCF-type E3 ubiquitin ligase complex. Four isoforms of FBL18 exist due to alternative splicing. |
| 免疫原 | KLH conjugated synthetic peptide: human FBXL18 |
| 抗原种属 | Human |
| 基因名称 | FBXL18 |
| 基因ID | |
| 蛋白名称 | F-box/LRR-repeat protein 18 |
| Uniprot ID | |
| 功能 | FBXL18 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
| 分子量 | Theoretical: 88 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |