Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)

Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

规格	价格/CNY		数量
100 μg	￥ 3,400	5日内发货
500 μg	￥ 13,600	5日内发货
1 mg	￥ 22,700	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 3,400

5日内发货

500 μg

￥ 13,600

5日内发货

1 mg

￥ 22,700

5日内发货

产品描述

种属	Mouse
表达系统	HEK293
标签	C-hFc
蛋白编号	P03953-1
别名	C3 convertase activator, AMBP-1, PFD, FACTOR D, CFD, ADN, EC 3.4.21.46, Complement factor D, DF, EC 3.4.21, Adipsin
蛋白构建	Recombinant Mouse Complement Factor D/CFD Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Ile26-Ser259.[Accession \|P03953-1]
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	The protein has a predicted MW of 52.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

内毒素	Less than 1EU per μg by the LAL method.
缓冲液	Supplied as 0.22μm filtered solution in 20mM Tris,500mM NaCl (pH 7.4).
存储	Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.