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PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)
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货号 TMPK-01290
别名 PD-L2, PDL2, PDCD1LG2, PDCD1L2, CD273, PDCD1 ligand 2, Butyrophilin B7-DC, Btdc, bA574F11.2, B7DC
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.73 kDa and the accession number is A0A2K5U5Z4.
其他形式的 “PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)”:
PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPK-01290 别名 PD-L2, PDL2, PDCD1LG2, PDCD1L2, CD273, PDCD1 ligand 2, Butyrophilin B7-DC, Btdc, bA574F11.2, B7DC
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.73 kDa and the accession number is A0A2K5U5Z4.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 313 | 6-8日内发货 | |
| 10 μg | ¥ 498 | 6-8日内发货 | |
| 20 μg | ¥ 793 | 5日内发货 | |
| 50 μg | ¥ 1,580 | 5日内发货 | |
| 100 μg | ¥ 2,660 | 5日内发货 | |
| 200 μg | ¥ 4,790 | 5日内发货 | |
| 500 μg | ¥ 10,600 | 5日内发货 |
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| 产品描述 | PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.73 kDa and the accession number is A0A2K5U5Z4. |
| 生物活性 | Cynomolgus PD-1, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus PD-L2, His Tag with an affinity constant of 0.17 μM as determined in SPR assay. |
| 研究背景 | PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. |
| 种属 | Cynomolgus |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | A0A2K5U5Z4 |
| 蛋白构建 | Leu20-Thr220 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | PD-L2, PDL2, PDCD1LG2, PDCD1L2, CD273, PDCD1 ligand 2, Butyrophilin B7-DC, Btdc, bA574F11.2, B7DC |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 23.73 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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