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Anti-DNase I Antibody (4N202)

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产品编号 TMAY-02628

Anti-DNase I Antibody (4N202) 是一种 Rabbit 抗体,靶向 DNase I。Anti-DNase I Antibody (4N202) 可用于 ELISA。

Anti-DNase I Antibody (4N202)

Anti-DNase I Antibody (4N202)

Rating icon 还可以
产品编号 TMAY-02628

Anti-DNase I Antibody (4N202) 是一种 Rabbit 抗体,靶向 DNase I。Anti-DNase I Antibody (4N202) 可用于 ELISA。

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产品介绍

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产品描述
Anti-DNase I Antibody (4N202) is a Rabbit antibody targeting DNase I. Anti-DNase I Antibody (4N202) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
4N202
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human DNase1 / Deoxyribonuclease I / DNL1 (rh DNase1 / Deoxyribonuclease I / DNL1; TMPY-03855; P24855; Met1-Lys282).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. DNaseI binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. Mutations in DNase1 gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. DNase1 is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human DNase1 / Deoxyribonuclease I / DNL1 Protein (TMPY-03855)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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