Sulfaquinoxaline sodium salt

Name: Sulfaquinoxaline sodium salt
Brand: TargetMol
SKU: T0917
Price: 138 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.72%

货号 T0917Cas号 967-80-6

别名 磺胺喹啉钠, 磺胺喹恶啉钠盐, Sulfaquinoxaline sodium, SQ-Na

Sulfaquinoxaline sodium salt (SQ-Na) 是一种兽用广谱抗菌剂，有抗革兰氏阴性菌和革兰氏阳性菌活性。Sulfaquinoxaline 能用于预防球虫病和细菌感染。

Sulfaquinoxaline sodium salt

一键复制产品信息

很棒

纯度: 99.72%

货号 T0917 别名 磺胺喹啉钠, 磺胺喹恶啉钠盐, Sulfaquinoxaline sodium, SQ-NaCas号 967-80-6

Sulfaquinoxaline sodium salt (SQ-Na) 是一种兽用广谱抗菌剂，有抗革兰氏阴性菌和革兰氏阳性菌活性。Sulfaquinoxaline 能用于预防球虫病和细菌感染。

规格	价格	库存
100 mg	¥ 163	现货
500 mg	¥ 278	现货
1 mL x 10 mM (in DMSO)	¥ 138	现货

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纯度: 99.72%

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COA LCMS HNMR 产品操作手册

产品介绍

Sulfaquinoxaline sodium salt AI Summary

Sulfaquinoxaline sodium salt exhibits a range of biological activities against various targets and pathogens. It demonstrates inhibitory activity against Mycobacterium Tuberculosis in 7H9 Media with IC50 values of 26370.0 nM and 23720.0 nM. In Drosophila S3 cells, it modulates lipid storage with a potency of 1158.2 nM. The compound activates Cytochrome P450 3A4 with a potency of 25118.9 nM and inhibits Aldehyde Dehydrogenase 1 (ALDH1A1) at 39810.7 nM. Additionally, it inhibits 15-human lipoxygenase 2 (15-hLO-2) with a potency of 15848.9 nM, induces DNA re-replication in SW480 colon adenocarcinoma cells at 31622.8 nM, and inhibits USP1/UAF1 at 12589.3 nM. It also inhibits PTHR, showing a potency of 100000.0 nM, and demonstrates antiviral activity against Foot and Mouth Disease Virus with potencies ranging from 12589.3 nM to 39810.7 nM. At a concentration of 10 µM, Sulfaquinoxaline sodium salt inhibits sodium fluorescein uptake in OATP1B1-transfected CHO cells by 73.75% and in OATP1B3-transfected CHO cells by 102.86%. The compound has no significant inhibition of cell viability in Vero E6 cells infected with SARS-CoV-2 strain BavPat1, with an inhibition index of -0.000446, indicating low bioactivity against the virus in this assay. However, Sulfaquinoxaline sodium salt exhibits antiviral activity by inhibiting SARS-CoV-2 induced cytotoxicity of Caco-2 cells at a 10 µM concentration over 48 hours, achieving an inhibition rate of 3.08%. It also demonstrates 23.54% inhibition of SARS-CoV-2 3CL-Pro protease at 20 µM, as assessed by fluorescence resonance energy transfer (FRET) with a peptide substrate. Additionally, it inhibits SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 µM concentration with an inhibition rate of -0.02% after a 48-hour exposure to 0.01 MOI SARS-CoV-2 virus, as determined by high-content imaging..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Sulfaquinoxaline sodium salt (SQ-Na) is a veterinary broad-spectrum antimicrobial agent with antigram-negative and gram-positive activity.Sulfaquinoxaline can be used to prevent coccidiosis and bacterial infections.
别名	磺胺喹啉钠, 磺胺喹恶啉钠盐, Sulfaquinoxaline sodium, SQ-Na

化学信息

分子量	322.32
分子式	C₁₄H₁₁N₄NaO₂S
CAS No.	967-80-6
Smiles	[Na+].Nc1ccc(cc1)S(=O)(=O)[N-]c1cnc2ccccc2n1
密度	no data available
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (186.15 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1025 mL	15.5125 mL	31.0251 mL	155.1253 mL
5 mM	0.6205 mL	3.1025 mL	6.2050 mL	31.0251 mL
10 mM	0.3103 mL	1.5513 mL	3.1025 mL	15.5125 mL
20 mM	0.1551 mL	0.7756 mL	1.5513 mL	7.7563 mL
50 mM	0.0621 mL	0.3103 mL	0.6205 mL	3.1025 mL
100 mM	0.0310 mL	0.1551 mL	0.3103 mL	1.5513 mL