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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-mouse CD45 Antibody (6A619)

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货号 TMAB-08954

Anti-mouse CD45 Antibody (6A619) 是一种 Rat 抗体，靶向 mouse CD45。Anti-mouse CD45 Antibody (6A619) 可用于 FCM。

Anti-mouse CD45 Antibody (6A619)

Anti-mouse CD45 Antibody (6A619)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08954

Anti-mouse CD45 Antibody (6A619) 是一种 Rat 抗体，靶向 mouse CD45。Anti-mouse CD45 Antibody (6A619) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,865
5日内发货
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产品介绍

生物活性
产品描述
Anti-mouse CD45 Antibody (6A619) is a Rat antibody targeting mouse CD45. Anti-mouse CD45 Antibody (6A619) can be used in FCM.
Ig Type
Rat IgG2b, k
克隆号
6A619
反应种属
Mouse
应用FCM
推荐剂量
FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rat
亚细胞定位Membrane; Single-pass type I membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling
抗原信息
基因名称
PTPRC
基因ID
5788
蛋白名称
Receptor-type tyrosine-protein phosphatase C
功能
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
化学信息
分子量Theoretical: 143 kDa. Actual: 220 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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