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别名 TMS1, Target of methylation-induced silencing 1, PYD and CARD domain-containing protein, PYCARD, hASC, Caspase recruitment domain-containing protein 5, CARD5, ASC, Apoptosis-associated speck-like protein containing a CARD
Anti-PYCARD Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 PYCARD。Anti-PYCARD Polyclonal Antibody 3 可用于 WB。
Anti-PYCARD Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 PYCARD。Anti-PYCARD Polyclonal Antibody 3 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-PYCARD Polyclonal Antibody 3 is a Rabbit antibody targeting PYCARD. Anti-PYCARD Polyclonal Antibody 3 can be used in WB. |
| 别名 | TMS1, Target of methylation-induced silencing 1, PYD and CARD domain-containing protein, PYCARD, hASC, Caspase recruitment domain-containing protein 5, CARD5, ASC, Apoptosis-associated speck-like protein containing a CARD |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat |
| 验证活性 | Sample: Lane 1: Mouse LympHnode tissue lysates Lane 2: Mouse Lung tissue lysates Lane 3: Mouse Spleen tissue lysates Lane 4: Rat LympHnode tissue lysates Lane 5: Rat Lung tissue lysates Lane 6: Rat Spleen tissue lysates Primary: Anti-ASC/TMS1 (TMAB-01597) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kDa Observed band size: 24 kDa ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Note=Upstream of caspase activation, a redistribution from the cytoplasm to the aggregates occurs. These appear as hollow, perinuclear spherical, ball-like structures. |
| 组织特异性 | Widely expressed at low levels. Detected in peripheral blood leukocytes, lung, small intestine, spleen, thymus, colon and at lower levels in placenta, liver and kidney. Very low expression in skeletal muscle, heart and brain. Detected in the leukemia cell |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 免疫原 | Recombinant Protein: mouse PYCARD protein |
| 抗原种属 | Mouse |
| 基因名称 | PYCARD |
| 蛋白名称 | Apoptosis-associated speck-like protein containing a CARD |
| 研究领域 | Tumor biomarkers,Associated Proteins,CARD Family |
| 功能 | Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. |
| 分子量 | Theoretical: 22 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |