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Anti-Menin Antibody (3A208)

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货号 TMAB-08749

Anti-Menin Antibody (3A208) 是一种 Rabbit 抗体,靶向 Menin。Anti-Menin Antibody (3A208) 可用于 WB,IP。

Anti-Menin Antibody (3A208)

Anti-Menin Antibody (3A208)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08749

Anti-Menin Antibody (3A208) 是一种 Rabbit 抗体,靶向 Menin。Anti-Menin Antibody (3A208) 可用于 WB,IP。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-Menin Antibody (3A208) is a Rabbit antibody targeting Menin. Anti-Menin Antibody (3A208) can be used in WB,IP.
Ig Type
IgG
克隆号
3A208
反应种属
Human
应用WBIP
推荐剂量
WB: 1:500-2000; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation.
组织特异性Ubiquitous.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression.
抗原信息
免疫原
A synthesized peptide: human Menin
抗原种属
Human
基因名称
MEN1
基因ID
蛋白名称
MCM3
Uniprot ID
功能
Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
化学信息
分子量Theoretical: 68 kDa. Actual: 68 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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