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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ACTH (18-39) Polyclonal Antibody

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货号 TMAB-02253

Anti-ACTH (18-39) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ACTH (18-39)。Anti-ACTH (18-39) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ACTH (18-39) Polyclonal Antibody

Anti-ACTH (18-39) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02253

Anti-ACTH (18-39) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ACTH (18-39)。Anti-ACTH (18-39) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-ACTH (18-39) Polyclonal Antibody is a Rabbit antibody targeting ACTH (18-39). Anti-ACTH (18-39) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性ACTH and MSH are produced by the pituitary gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human ACTH
抗原种属
Human
基因名称
POMC
基因ID
5443
蛋白名称
Pro-opiomelanocortin
Uniprot ID
P01189
功能
ACTH stimulates the adrenal glands to release cortisol.
MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.
Beta-endorphin and Met-enkephalin are endogenous opiates.
化学信息
分子量Theoretical: 2.5/4.5 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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