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别名 PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
GDF-15 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. The accession number is Q99988-1.


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GDF-15 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. The accession number is Q99988-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 389 | 6-8日内发货 | |
| 10 μg | ¥ 628 | 6-8日内发货 | |
| 20 μg | ¥ 987 | 5日内发货 | |
| 50 μg | ¥ 1,980 | 5日内发货 | |
| 100 μg | ¥ 3,430 | 5日内发货 | |
| 200 μg | ¥ 5,790 | 5日内发货 | |
| 500 μg | ¥ 11,500 | 5日内发货 |
| 产品描述 | GDF-15 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. The accession number is Q99988-1. |
| 生物活性 | Immobilized Human GDF15, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 11.5 ng/ml determined by ELISA. Human GFRAL, hFc Tag captured on CM5 Chip via Protein A can bind Human GDF15, His Tag with an affinity constant of 0.014 nM as determined in SPR assay (Biacore T200). |
| 研究背景 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-His |
| 蛋白编号 | Q99988-1 |
| 蛋白构建 | Ala197-Ile308 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in 50 mM HAc (pH 2.9). Normally 8% trehalose is added as protectant before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15 |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 13.5 kDa (Predicted); 15-16 kDa (reducing conditions) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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