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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KDELR3 Polyclonal Antibody

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货号 TMAB-07970

Anti-KDELR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KDELR3。Anti-KDELR3 Polyclonal Antibody 可用于 WB。

Anti-KDELR3 Polyclonal Antibody

Anti-KDELR3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07970

Anti-KDELR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KDELR3。Anti-KDELR3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-KDELR3 Polyclonal Antibody is a Rabbit antibody targeting KDELR3. Anti-KDELR3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human KDELR3
抗原种属
Human
基因名称
KDELR3
基因ID
11015
蛋白名称
ER lumen protein-retaining receptor 3
Uniprot ID
O43731
功能
KDELR3 is required for the retention of luminal endoplasmic reticulum proteins. It determines the specificity of the luminal ER protein retention system and is also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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