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Anti-ADAMTS13 Antibody (1C436)
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产品编号 TMAC-00087
别名 vWFCP, vWF-cleaving protease), von Willebrand factor-cleaving protease (vWF-CP, Gm710, ADAMTS-13, ADAM-TS13, Adamts13, ADAM-TS 13
Anti-ADAMTS13 Antibody (1C436) 是一种 Rabbit 抗体，靶向 ADAMTS13。Anti-ADAMTS13 Antibody (1C436) 可用于 WB,IHC,FCM。
Anti-ADAMTS13 Antibody (1C436)
Anti-ADAMTS13 Antibody (1C436)
还可以产品编号 TMAC-00087 别名 vWFCP, vWF-cleaving protease), von Willebrand factor-cleaving protease (vWF-CP, Gm710, ADAMTS-13, ADAM-TS13, Adamts13, ADAM-TS 13
Anti-ADAMTS13 Antibody (1C436) 是一种 Rabbit 抗体，靶向 ADAMTS13。Anti-ADAMTS13 Antibody (1C436) 可用于 WB,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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抗原信息
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| 产品描述 | Anti-ADAMTS13 Antibody (1C436) is a Rabbit antibody targeting ADAMTS13. Anti-ADAMTS13 Antibody (1C436) can be used in WB,IHC,FCM. |
| 别名 | vWFCP, vWF-cleaving protease), von Willebrand factor-cleaving protease (vWF-CP, Gm710, ADAMTS-13, ADAM-TS13, Adamts13, ADAM-TS 13 |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of ADAMTS13 on SiHa cell (1), PC-3M cell (2) and A549 cell lysates using anti-ADAMTS13 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ADAMTS13 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-ADAMTS13 antibody. Counter stained with hematoxylin. 4. Flow cytometric analysis of HepG2 cells with ADAMTS13 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)??also known as von Willebrand factor-cleaving protease (VWFCP)??is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. Glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: human ADAMTS13 aa 150-350 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 154 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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