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Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2

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产品编号 TMAB-10887

Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-ITGB2 (Thr758)。Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2

Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10887

Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-ITGB2 (Thr758)。Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ITGB2 (Thr758). Anti-Phospho-ITGB2 (Thr758) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
交叉反应
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human CD18 around the phosphorylation site of Thr758
抗原种属
Human
基因名称
ITGB2
基因ID
蛋白名称
Integrin beta-2
Uniprot ID
功能
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.
化学信息
分子量Theoretical: 82 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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