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Anti-Glucocorticoid receptor Antibody (5H652)

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货号 TMAB-06534

Anti-Glucocorticoid receptor Antibody (5H652) 是一种 Rabbit 抗体,靶向 Glucocorticoid receptor。Anti-Glucocorticoid receptor Antibody (5H652) 可用于 WB,FCM。

Anti-Glucocorticoid receptor Antibody (5H652)

Anti-Glucocorticoid receptor Antibody (5H652)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06534

Anti-Glucocorticoid receptor Antibody (5H652) 是一种 Rabbit 抗体,靶向 Glucocorticoid receptor。Anti-Glucocorticoid receptor Antibody (5H652) 可用于 WB,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-Glucocorticoid receptor Antibody (5H652) is a Rabbit antibody targeting Glucocorticoid receptor. Anti-Glucocorticoid receptor Antibody (5H652) can be used in WB,FCM.
Ig Type
IgG
克隆号
5H652
反应种属
Human,Mouse,Rat
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand, nuclear after ligand-binding. Isoform Beta: Nucleus. Note=Localized largely in the nucleus.
组织特异性Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors.
抗原信息
免疫原
A synthesized peptide: human Glucocorticoid receptor
抗原种属
Human
基因名称
NR3C1
基因ID
蛋白名称
Glucocorticoid receptor
Uniprot ID
功能
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
化学信息
分子量Theoretical: 86 kDa. Actual: 95 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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