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Anti-Glucocorticoid receptor Antibody (5H652) 是一种 Rabbit 抗体,靶向 Glucocorticoid receptor。Anti-Glucocorticoid receptor Antibody (5H652) 可用于 WB,FCM。
Anti-Glucocorticoid receptor Antibody (5H652) 是一种 Rabbit 抗体,靶向 Glucocorticoid receptor。Anti-Glucocorticoid receptor Antibody (5H652) 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-Glucocorticoid receptor Antibody (5H652) is a Rabbit antibody targeting Glucocorticoid receptor. Anti-Glucocorticoid receptor Antibody (5H652) can be used in WB,FCM. |
| Ig Type | IgG |
| 克隆号 | 5H652 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand, nuclear after ligand-binding. Isoform Beta: Nucleus. Note=Localized largely in the nucleus. |
| 组织特异性 | Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. |
| 免疫原 | A synthesized peptide: human Glucocorticoid receptor |
| 抗原种属 | Human |
| 基因名称 | NR3C1 |
| 基因ID | |
| 蛋白名称 | Glucocorticoid receptor |
| Uniprot ID | |
| 功能 | Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation. |
| 分子量 | Theoretical: 86 kDa. Actual: 95 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |