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Anti-IGSF1 Polyclonal Antibody

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货号 TMAB-07565

Anti-IGSF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IGSF1。Anti-IGSF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-IGSF1 Polyclonal Antibody

Anti-IGSF1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07565

Anti-IGSF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IGSF1。Anti-IGSF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-IGSF1 Polyclonal Antibody is a Rabbit antibody targeting IGSF1. Anti-IGSF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoforms 1 and 2: Membrane; Multipass membrane protein (Potential). Isoform 3: Secreted.
组织特异性Highly expressed in pancreas, testis and fetal liver. Moderately expressed in heart, prostate and small intestine. Expressed at very low levels in brain, thymus, ovary, colon, fetal lung and fetal kidney. Expressed in muscle. Isoform 3 is expressed in pituitary gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景IGSF1 is a highly glycolylated immunoglobulin domain-containing protein. IGSF1 has been shown to act as a coreceptor in inhibin signaling, however, it does not appear to be a high-affinity inhibin receptor by itself. May reduce or inhibit activin A signaling and is believed to be necessary in the mediation of specific effects of inhibin B on activin-stimulated transcription. IGSF1 has been found to interact with several members of the ACVR family and possibly some members of the BMPR group. There are 3 known isoforms of IGSF1, with 1 and 2 likely being multi-pass membrane proteins. Isoform 3 is believed to be expressed as a secreted form. Expression is high in pancreas, testis and fetal liver, while heart, prostate and small intestine show only moderate expression. IGSF1 may be found at very low levels in brain, muscle, thymus, ovary, colon, fetal lung and fetal kidney. Isoform 3 has been detected in pituitary gland.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IGSF1
抗原种属
Human
基因名称
IGSF1
基因ID
蛋白名称
Immunoglobulin superfamily member 1
Uniprot ID
功能
Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B (By similarity). Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription.
化学信息
分子量Theoretical: 80, 144 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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