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Anti-Renin Antibody (1Q991)

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Anti-Renin Antibody (1Q991)
产品编号 TMAY-03207
别名 renin, REN, HNFJ2, FLJ10761

Anti-Renin Antibody (1Q991) 是一种 Rabbit 抗体,靶向 Renin。Anti-Renin Antibody (1Q991) 可用于 ELISA,IHC-P。

Anti-Renin Antibody (1Q991)
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Anti-Renin Antibody (1Q991)

Rating icon 还可以
Anti-Renin Antibody (1Q991)
产品编号 TMAY-03207 别名 renin, REN, HNFJ2, FLJ10761

Anti-Renin Antibody (1Q991) 是一种 Rabbit 抗体,靶向 Renin。Anti-Renin Antibody (1Q991) 可用于 ELISA,IHC-P。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-Renin Antibody (1Q991) is a Rabbit antibody targeting Renin. Anti-Renin Antibody (1Q991) can be used in ELISA,IHC-P.
别名renin, REN, HNFJ2, FLJ10761
Ig Type
Rabbit IgG
克隆号
1Q991
交叉反应
Mouse
验证活性
Immunochemical staining of mouse REN1 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to juxtaglomerular cell. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
应用
ELISA,IHC-P
推荐剂量
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse REN1 (rM REN1; TMPY-01231; NP_112469.1; Met 1-Arg 402).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse REN1 protein (TMPY-01231)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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