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Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 2
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产品编号 TMAC-00443
别名 Siglec-2/CD22 (p-Y807), Siglec-2/CD22 (p-Tyr807), p-Siglec-2/CD22 (Y807), p-Siglec-2/CD22 (Tyr807)
Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Siglec-2/CD22 (Tyr807)。Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 可用于 WB。
Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 2
Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 2
还可以产品编号 TMAC-00443 别名 Siglec-2/CD22 (p-Y807), Siglec-2/CD22 (p-Tyr807), p-Siglec-2/CD22 (Y807), p-Siglec-2/CD22 (Tyr807)
Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Siglec-2/CD22 (Tyr807)。Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,240 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Siglec-2/CD22 (Tyr807). Anti-Phospho-Siglec-2/CD22 (Tyr807) Polyclonal Antibody can be used in WB. |
| 别名 | Siglec-2/CD22 (p-Y807), Siglec-2/CD22 (p-Tyr807), p-Siglec-2/CD22 (Y807), p-Siglec-2/CD22 (Tyr807) |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of extracts from COS7 cells (Lane 2), using BL-CAM (Phospho-Tyr807) Antibody TMAC-00443. The lane on the left is treated with antigen-specific peptide. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | Peptide sequence around phosphorylation site of tyrosine 807 (G-D-Y(p)-E-N) derived from Human BL-CAM |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Actual: 95 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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