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Cadherin 17/CDH17 Protein, Rhesus macaque, Recombinant (His)

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产品编号 TMPK-00473

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 85.60 kDa and the accession number is A0A1D5R2B4.

Cadherin 17/CDH17 Protein, Rhesus macaque, Recombinant (His)

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产品编号 TMPK-00473

规格	价格	库存
5 μg	¥ 358	6-8日内发货
10 μg	¥ 573	6-8日内发货
20 μg	¥ 938	5日内发货
50 μg	¥ 1,830	5日内发货
100 μg	¥ 3,100	5日内发货
200 μg	¥ 5,620	5日内发货
500 μg	¥ 12,400	5日内发货

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产品信息

生物活性	Immobilized Rhesus macaque CDH17, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 9.5ng/ml determined by ELISA.
产品描述	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 85.60 kDa and the accession number is A0A1D5R2B4.
种属	Rhesus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	A0A1D5R2B4
别名	P130,MGC142024,MGC138218,LI-cadherin,HPT-1,FLJ26931,Cdh17,CDH16,Cadherin-17,cadherin-16,BILL-cadherin
蛋白构建	Gln23-Thr784
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	85.60 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 150 mM NaCl (pH 8.0). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.