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Anti-BNIP3L Antibody (1F355)

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货号 TMAB-03180

Anti-BNIP3L Antibody (1F355) 是一种 Rabbit 抗体，靶向 BNIP3L。Anti-BNIP3L Antibody (1F355) 可用于 IHC-P,IHC-Fr,IF。

Anti-BNIP3L Antibody (1F355)

Anti-BNIP3L Antibody (1F355)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03180

Anti-BNIP3L Antibody (1F355) 是一种 Rabbit 抗体，靶向 BNIP3L。Anti-BNIP3L Antibody (1F355) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-BNIP3L Antibody (1F355) is a Rabbit antibody targeting BNIP3L. Anti-BNIP3L Antibody (1F355) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
1F355
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-pass membrane protein (Potential). Note=Colocalizes with SPATA18 at the mitochondrion outer membrane.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3.
抗原信息
免疫原
A synthesized peptide: human BNIP3L
抗原种属
Human
基因名称
BNIP3L
基因ID
665
蛋白名称
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Uniprot ID
O60238
功能
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
化学信息
分子量Theoretical: 24 kDa. Actual: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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