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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD40 Monoclonal Antibody (1R963)

Synonyms: TNFRSF5, p50, CDW40, Bp50
货号 TMAT-0414 一键复制产品信息
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Anti-CD40 Monoclonal Antibody (1R963) 是一种 Mouse 抗体，靶向 CD40。Anti-CD40 Monoclonal Antibody (1R963) 可用于 WB,IHC,FCM。

Anti-CD40 Monoclonal Antibody (1R963)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0414

别名 TNFRSF5, p50, CDW40, Bp50

Anti-CD40 Monoclonal Antibody (1R963) 是一种 Mouse 抗体，靶向 CD40。Anti-CD40 Monoclonal Antibody (1R963) 可用于 WB,IHC,FCM。

Anti-CD40 Monoclonal Antibody (1R963)
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产品介绍

生物活性
产品描述
Anti-CD40 Monoclonal Antibody (1R963) is a Mouse antibody targeting CD40. Anti-CD40 Monoclonal Antibody (1R963) can be used in WB,IHC,FCM.
别名
TNFRSF5, p50, CDW40, Bp50
Ig Type
IgG1
克隆号
1R963
反应种属
Human
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD40 (AA: extra(21-193)) expressed in E. Coli.
抗原种属
Human
基因名称
CD40
基因ID
958
蛋白名称
Tumor necrosis factor receptor superfamily member 5
Uniprot ID
P25942
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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