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顶部生物活性储存和溶解信息计算器

Anti-KLHL22 Antibody (5K493)

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Anti-KLHL22 Antibody (5K493)
产品编号 TMAC-02332
别名 RGD1306288, Klhl 22, KLH22_HUMAN, Kelch-like protein 22, kelch-like family member 22, kelch-like 22, KELCHL, 2610318I18Rik

Anti-KLHL22 Antibody (5K493) 是一种 Mouse 抗体，靶向 KLHL22。Anti-KLHL22 Antibody (5K493) 可用于 WB,ICC。

Anti-KLHL22 Antibody (5K493)

Anti-KLHL22 Antibody (5K493)

Rating icon 还可以
Anti-KLHL22 Antibody (5K493)
产品编号 TMAC-02332 别名 RGD1306288, Klhl 22, KLH22_HUMAN, Kelch-like protein 22, kelch-like family member 22, kelch-like 22, KELCHL, 2610318I18Rik

Anti-KLHL22 Antibody (5K493) 是一种 Mouse 抗体，靶向 KLHL22。Anti-KLHL22 Antibody (5K493) 可用于 WB,ICC。

规格价格库存数量
50 μL
¥ 1,980
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-KLHL22 Antibody (5K493) is a Mouse antibody targeting KLHL22. Anti-KLHL22 Antibody (5K493) can be used in WB,ICC.
别名RGD1306288, Klhl 22, KLH22_HUMAN, Kelch-like protein 22, kelch-like family member 22, kelch-like 22, KELCHL, 2610318I18Rik
克隆号
5K493
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of KLHL22 on mouse brain tissue lysate using anti-KLHL22 antibody at 1/1,000 dilution.
2. ICC staining KLHL22 (green) and actin filaments (red) in U251 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC
推荐剂量
WB: 1:500; ICC: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
研究背景Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q53GT1
化学信息
分子量Theoretical: 72 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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