Name: LRG1 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-03965
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 683

6-8日内发货

10 μg

¥ 1,130

6-8日内发货

20 μg

¥ 1,930

5日内发货

50 μg

¥ 4,430

5日内发货

生物活性

产品描述	LRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.3 kDa and the accession number is AAH34389.1.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. It contains 4 LIM zinc-binding domains and 1 Rho-GAP domain. LRG1 is involved in promoting neovascularization (new blood vessel growth) by causing a switch in transforming growth factor-beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. It may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Diseases associated with LRG1 include Appendicitis and Normal Pressure Hydrocephalus.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	AAH34389.1
蛋白构建	A DNA sequence encoding the human LRG1 (AAH34389.1) (Met1-Gln347) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Val 36
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	LRG, leucine-rich α-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein 1, HMFT1766
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	61.3 kDa (predicted); 65-75 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

LRG1 Protein, Human, Recombinant (hFc)

LRG1 Protein, Human, Recombinant (hFc)

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