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Anti-ATM Antibody (9B624) 是一种 Rabbit 抗体,靶向 ATM。Anti-ATM Antibody (9B624) 可用于 WB,ICC/IF,IHC。
Anti-ATM Antibody (9B624) 是一种 Rabbit 抗体,靶向 ATM。Anti-ATM Antibody (9B624) 可用于 WB,ICC/IF,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-ATM Antibody (9B624) is a Rabbit antibody targeting ATM. Anti-ATM Antibody (9B624) can be used in WB,ICC/IF,IHC. |
别名 | telomere maintenance 1, Telomere fusion protein, TELO1, TEL1, Tefu, Serine/threonine-protein kinase ATM, Serine protein kinase ATM, OTTHUMP00000232981, MGC74674, homolog, DKFZp781A0353, ATM serine/threonine kinase, ATE, ATDC, ATD, ATC, Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated, ATA, AT1, A-T mutated homolog, A-T mutated, AT mutated |
Ig Type | IgG |
克隆号 | 9B624 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of ATM on CRC cell lysates using anti-ATM antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-ATM antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-ATM antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-ATM antibody. Counter stained with hematoxylin. 5. ICC staining ATM in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining ATM in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining ATM in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy-termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiec-tases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 350 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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