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Anti-GNS Antibody (8V673)

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Anti-GNS Antibody (8V673)
产品编号 TMAY-00605
别名 N-Acetylglucosamine-6-Sulfatase, GNS, Glucosamine-6-Sulfatase, G6S

Anti-GNS Antibody (8V673) 是一种 Mouse 抗体,靶向 GNS。Anti-GNS Antibody (8V673) 可用于 ELISA。

Anti-GNS Antibody (8V673)

Anti-GNS Antibody (8V673)

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Anti-GNS Antibody (8V673)
产品编号 TMAY-00605 别名 N-Acetylglucosamine-6-Sulfatase, GNS, Glucosamine-6-Sulfatase, G6S

Anti-GNS Antibody (8V673) 是一种 Mouse 抗体,靶向 GNS。Anti-GNS Antibody (8V673) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-GNS Antibody (8V673) is a Mouse antibody targeting GNS. Anti-GNS Antibody (8V673) can be used in ELISA.
别名N-Acetylglucosamine-6-Sulfatase, GNS, Glucosamine-6-Sulfatase, G6S
Ig Type
Mouse IgG2b
克隆号
8V673
交叉反应
Human
应用
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GNS / G6S (rhGNS; NP_002067.1Met 1-Leu 552). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Glucosamine (N-acetyl)-6-sulfatase (GNS), also known as G6S, a hydrolase, which is one of the enzymes involved in heparan sulfate catabolism leading to lysosomal storage. GNS is required for the catabolism of the glycosaminoglycans (GAG) including heparin, heparan sulfate, and keratan sulfate through the hydrolysis of the 6-sulfate group from the N-acetyl-D-glucosamine 6-sulfate units. Mucopolysaccharidosis type IIID (MPS IIID) is the least common of the four subtypes of Sanfilippo syndrome. It is caused by a deficiency of N-acetylglucosamine-6-sulphatase. A mutation in GNS resulting in MPS IIID indicates the potential utility of molecular diagnosis for this rare condition. As the least common type of the four subtypes of Sanfilippo syndrome, MPS IIID has profound mental deterioration, hyperactivity, and relatively mild somatic manifestations.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Human cell-derived rhGNS
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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