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Anti-ESAM Antibody (1G734)
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产品编号 TMAY-00423
别名 endothelial cell adhesion molecule
Anti-ESAM Antibody (1G734) 是一种 Mouse 抗体，靶向 ESAM。Anti-ESAM Antibody (1G734) 可用于 ELISA。
Anti-ESAM Antibody (1G734)
331 Anti-ESAM Antibody (1G734)
还可以产品编号 TMAY-00423 别名 endothelial cell adhesion molecule
Anti-ESAM Antibody (1G734) 是一种 Mouse 抗体，靶向 ESAM。Anti-ESAM Antibody (1G734) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-ESAM Antibody (1G734) is a Mouse antibody targeting ESAM. Anti-ESAM Antibody (1G734) can be used in ELISA. |
| 别名 | endothelial cell adhesion molecule |
| Ig Type | Mouse IgG1 |
| 克隆号 | 1G734 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human extracellular domain (rh ESAM; TMPY-01312; NP_620411.2; Met 1-Ala 248). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human ESAM protein (TMPY-01312) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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