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顶部生物活性储存和溶解信息计算器

Anti-Complement C5 Antibody (2J123)

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产品编号 TMAH-00129

别名 ECLZB, CPAMD4, complement component 5, Complement C5, C5D, C5b, C5a

Anti-Complement C5 Antibody (2J123) 是一种抗体，靶向 Complement C5。Anti-Complement C5 Antibody (2J123) 可用于 ELISA,FCM。

Anti-Complement C5 Antibody (2J123)

Anti-Complement C5 Antibody (2J123)

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产品编号 TMAH-00129 别名 ECLZB, CPAMD4, complement component 5, Complement C5, C5D, C5b, C5a

Anti-Complement C5 Antibody (2J123) 是一种抗体，靶向 Complement C5。Anti-Complement C5 Antibody (2J123) 可用于 ELISA,FCM。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-Complement C5 Antibody (2J123) is an antibody targeting Complement C5. Anti-Complement C5 Antibody (2J123) can be used in ELISA,FCM.
别名ECLZB, CPAMD4, complement component 5, Complement C5, C5D, C5b, C5a
Ig Type
Mouse IgG2a
克隆号
2J123
交叉反应
Human
验证活性
Overlay Peak curve showing Hela cells surface stained with TMAH-00129 (red line) at 1:800. Then 10% normal goat serum was Incubated to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10, 021 events was performed.
应用ELISAFCM
推荐剂量
FCM:1:20-1:500.
抗体种类
Monoclonal
亚细胞定位Secreted.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human C5 Protein
抗原种属
Human
基因名称
C5
基因ID
727
Uniprot ID
P01031
研究领域
Immunology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

CPAMD-4CPAMD 4

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