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Anti-ADAMTS8 Polyclonal Antibody

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货号 TMAB-00058

别名 METH8, METH2, METH 8, METH 2, ATS8, ADAMTS 8, ADAM TS8, ADAM TS 8, ADAM metallopeptidase with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8, A disintegrin and metalloproteinase with thrombospondin motifs 8

Anti-ADAMTS8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADAMTS8。Anti-ADAMTS8 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

Anti-ADAMTS8 Polyclonal Antibody

Anti-ADAMTS8 Polyclonal Antibody

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货号 TMAB-00058 别名 METH8, METH2, METH 8, METH 2, ATS8, ADAMTS 8, ADAM TS8, ADAM TS 8, ADAM metallopeptidase with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8, A disintegrin and metalloproteinase with thrombospondin motifs 8

Anti-ADAMTS8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADAMTS8。Anti-ADAMTS8 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADAMTS8 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS8. Anti-ADAMTS8 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
别名METH8, METH2, METH 8, METH 2, ATS8, ADAMTS 8, ADAM TS8, ADAM TS 8, ADAM metallopeptidase with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8, A disintegrin and metalloproteinase with thrombospondin motifs 8
Ig Type
IgG
反应种属
(predicted:Human,Mouse,Rat,Chicken,Dog,Pig,Horse)
应用ELISAIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix (By similarity).
组织特异性Highly expressed in adult and fetal lung, lower expression in brain, placenta, heart, stomach and fetal brain and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADAMTS8
抗原种属
Human
基因名称
ADAMTS8
基因ID
11095
蛋白名称
A disintegrin and metalloproteinase with thrombospondin motifs 8
功能
Has anti-angiogenic properties.
化学信息
分子量Theoretical: 74 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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