Anti-Integrin alpha 4 Antibody (4Z390) is a Rabbit antibody targeting Integrin alpha 4. Anti-Integrin alpha 4 Antibody (4Z390) can be used in WB.

IgG

4Z390

Human

25 μg total protein per lane of various lysates (see on figure) probed with Integrin alpha 4 monoclonal antibody, unconjugated (TMAB-07740) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.

WB: 1:500-2000

Monoclonal

A synthesized peptide: human Integrin alpha 4

Human

ITGA4

Integrin alpha-4

Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.