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Anti-BAG3 Antibody (9B703) 是一种 Rabbit 抗体,靶向 BAG3。Anti-BAG3 Antibody (9B703) 可用于 WB,IHC,IP。
Anti-BAG3 Antibody (9B703) 是一种 Rabbit 抗体,靶向 BAG3。Anti-BAG3 Antibody (9B703) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-BAG3 Antibody (9B703) is a Rabbit antibody targeting BAG3. Anti-BAG3 Antibody (9B703) can be used in WB,IHC,IP. |
别名 | MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3 |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of Bag3 on Hela (1) and MCF-7 (2) cell using anti-Bag3 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-Bag3 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The Bag family of proteins are characterized by the presence of a 45 amino acid Bag domain through which they bind with high affinity to the ATPase domain of HSP 70, thereby negatively regulating HSP 70 chaperone activity. Bag-3 (Bcl-2-associated athanogene 3), also known as BIS or CAIR-1, is a 575 amino acid protein that contains one C-terminal Bag domain and two N-terminal WW domains. Like other members of the Bag family, Bag-3 functions to inhibit the chaperone activity of HSP 70, specifically by promoting the release of HSP 70-bound substrates. Additionally, Bag-3 exhibits apoptotic activity via cell cycle control, suggesting a possible role for Bag-3 in tumor progression. The gene encoding Bag-3 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 75 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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