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别名 mitAAT, mAspAT, KYAT4, KATIV, KAT4, DEE82
Anti-GOT2 Antibody (2H61) 是一种 Mouse 抗体,靶向 GOT2。Anti-GOT2 Antibody (2H61) 可用于 IHC-P。
Anti-GOT2 Antibody (2H61) 是一种 Mouse 抗体,靶向 GOT2。Anti-GOT2 Antibody (2H61) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
| 产品描述 | Anti-GOT2 Antibody (2H61) is a Mouse antibody targeting GOT2. Anti-GOT2 Antibody (2H61) can be used in IHC-P. |
| 别名 | mitAAT, mAspAT, KYAT4, KATIV, KAT4, DEE82 |
| Ig Type | Mouse IgG1 |
| 克隆号 | 2H61 |
| 交叉反应 | Human |
| 特异性 | Human GOT2 |
| 验证活性 | 1. Immunochemical staining of human GOT2 in human liver with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human GOT2 in human hepatoma with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human GOT2. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | GOT2 (Glutamic-Oxaloacetic Transaminase 2) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein is a mitochondrial enzyme that oxidizes glutamate to produce alpha-ketoglutarate for the Krebs cycle, eventually leading to the production of adenosine triphosphate (ATP). GOT2 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. GOT2-mediated ATP synthesis may be a pivotal mechanism underlying the protective effect of febuxostat against neurodegeneration in experimental autoimmune encephalomyelitis (EAE). The high aberrant GOT2 expression is prognostic in diffuse large B-cell lymphoma. GOT2 is broadly expressed in the heart, liver, and other tissues. Diseases associated with GOT2 include Epileptic Encephalopathy, Early Infantile, 82, and Acute Vascular Insufficiency Of Intestine. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: C-terminus of the Human GOT2 |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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