Anti-GOT2 Antibody (2H61)

Name: Anti-GOT2 Antibody (2H61)
Brand: TargetMol
SKU: TMAY-00223
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00223

Anti-GOT2 Antibody (2H61) 是一种 Mouse 抗体，靶向 GOT2。Anti-GOT2 Antibody (2H61) 可用于 IHC-P。

Anti-GOT2 Antibody (2H61)

还可以

产品编号 TMAY-00223

Anti-GOT2 Antibody (2H61) 是一种 Mouse 抗体，靶向 GOT2。Anti-GOT2 Antibody (2H61) 可用于 IHC-P。

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生物活性

产品描述	Anti-GOT2 Antibody (2H61) is a Mouse antibody targeting GOT2. Anti-GOT2 Antibody (2H61) can be used in IHC-P.
Ig Type	Monoclonal Mouse IgG1
克隆号	2H61
交叉反应	Human
验证活性	1. Immunochemical staining of human GOT2 in human liver with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human GOT2 in human hepatoma with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).
应用	IHC-P
推荐剂量	IHC-P: 1:50-1:200
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human GOT2. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	GOT2 (Glutamic-Oxaloacetic Transaminase 2) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein is a mitochondrial enzyme that oxidizes glutamate to produce alpha-ketoglutarate for the Krebs cycle, eventually leading to the production of adenosine triphosphate (ATP). GOT2 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. GOT2-mediated ATP synthesis may be a pivotal mechanism underlying the protective effect of febuxostat against neurodegeneration in experimental autoimmune encephalomyelitis (EAE). The high aberrant GOT2 expression is prognostic in diffuse large B-cell lymphoma. GOT2 is broadly expressed in the heart, liver, and other tissues. Diseases associated with GOT2 include Epileptic Encephalopathy, Early Infantile, 82, and Acute Vascular Insufficiency Of Intestine.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	A synthetic peptide corresponding to the C-terminus of the Human GOT2
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.