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Anti-Carboxypeptidase B1 Antibody (8Y498)
还可以产品编号 TMAY-00905
Anti-Carboxypeptidase B1 Antibody (8Y498) 是一种 Mouse 抗体，靶向 Carboxypeptidase B1。Anti-Carboxypeptidase B1 Antibody (8Y498) 可用于 IHC-P。
Anti-Carboxypeptidase B1 Antibody (8Y498)
Anti-Carboxypeptidase B1 Antibody (8Y498)
还可以产品编号 TMAY-00905
Anti-Carboxypeptidase B1 Antibody (8Y498) 是一种 Mouse 抗体，靶向 Carboxypeptidase B1。Anti-Carboxypeptidase B1 Antibody (8Y498) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Carboxypeptidase B1 Antibody (8Y498) is a Mouse antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (8Y498) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8Y498 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human CPB1 in human pancreas with mouse monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:1000-1:4000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carboxypeptidase B1 / CPB1 (rh Carboxypeptidase B1 / CPB1; TMPY-00727; NP_001862.2; Met1-Tyr417). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Carboxypeptidase B1 / CPB1 protein (TMPY-00727) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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