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Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FHOD1 (Thr1141)。Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FHOD1 (Thr1141)。Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FHOD1 (Thr1141). Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic. |
| 组织特异性 | Ubiquitous. Highly expressed in spleen. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human FHOD1 around the phosphorylation site of Thr1141 |
| 抗原种属 | Human |
| 基因名称 | FHOD1 |
| 基因ID | |
| 蛋白名称 | FH1/FH2 domain-containing protein 1 |
| Uniprot ID | |
| 功能 | Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. |
| 分子量 | Theoretical: 126 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |