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Anti-LILRA4/CD85g Antibody (3H551)

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产品编号 TMAH-00698
别名 MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g

Anti-LILRA4/CD85g Antibody (3H551) 是一种抗体,靶向 LILRA4/CD85g。Anti-LILRA4/CD85g Antibody (3H551) 可用于 ELISA, WB, IHC。

Anti-LILRA4/CD85g Antibody (3H551)

Anti-LILRA4/CD85g Antibody (3H551)

Rating icon 还可以
产品编号 TMAH-00698 别名 MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g

Anti-LILRA4/CD85g Antibody (3H551) 是一种抗体,靶向 LILRA4/CD85g。Anti-LILRA4/CD85g Antibody (3H551) 可用于 ELISA, WB, IHC。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-LILRA4/CD85g Antibody (3H551) is an antibody targeting LILRA4/CD85g. Anti-LILRA4/CD85g Antibody (3H551) can be used in ELISA, WB, IHC.
别名MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g
Ig Type
hIgG1
克隆号
3H551
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in:Hela whole cell lysate (20µg), HpeG2 whole cell lysate (20µg), Jurkat whole cell lysate (20µg), K562 whole cell lysate (20µg)
-All lanes: LILRA4 antibody at 1:1000
-Secondary: Goat polyclonal to human IgG at 1/40000 dilution
-Predicted band size:55.18, 47.81 kDa
-Observed band size:50 kDa
-Exposure time:20s
2. IHC image of TMAH-00698 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
应用
ELISA, WB, IHC
推荐剂量
WB:1:500-1:2000; IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades. Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells. Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+). Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human LILRA4 Protein
抗原种属
Human
基因ID
23547
Uniprot ID
研究领域
Immunology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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