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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-ITGA4 Antibody (6M773)

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货号 TMAH-00642

别名 VLA-4 subunit alpha, ITGA 4, Integrin alpha-IV, Integrin alpha-4, CD49D, CD49 antigen-like family member D, CD antigen CD49d

Anti-ITGA4 Antibody (6M773) 是一种抗体，靶向 ITGA4。Anti-ITGA4 Antibody (6M773) 可用于 ELISA,WB。

Anti-ITGA4 Antibody (6M773)

Anti-ITGA4 Antibody (6M773)

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Rating icon 还可以
货号 TMAH-00642 别名 VLA-4 subunit alpha, ITGA 4, Integrin alpha-IV, Integrin alpha-4, CD49D, CD49 antigen-like family member D, CD antigen CD49d

Anti-ITGA4 Antibody (6M773) 是一种抗体，靶向 ITGA4。Anti-ITGA4 Antibody (6M773) 可用于 ELISA,WB。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-ITGA4 Antibody (6M773) is an antibody targeting ITGA4. Anti-ITGA4 Antibody (6M773) can be used in ELISA,WB.
别名VLA-4 subunit alpha, ITGA 4, Integrin alpha-IV, Integrin alpha-4, CD49D, CD49 antigen-like family member D, CD antigen CD49d
Ig Type
Rabbit IgG
克隆号
6M773
反应种属
Human
验证活性
Western Blot
-Positive WB detected in: Jurkat whole cell lysate
-All lanes: ITGA4 antibody at 1:1500
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 115, 26 kDa
-Observed band size: 140 kDa
应用ELISAWB
推荐剂量
WB:1:500-1:5000.
抗体种类
Monoclonal
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGA4:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Integrin alpha 4
抗原种属
Human
基因名称
ITGA4
基因ID
3676
Uniprot ID
P13612
研究领域
Cardiovascular, Immunology, Signal transduction, Stem cells
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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