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Anti-PPAR gamma/PPARG Antibody (2S691)

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货号 TMAC-03397

别名 PPAR-gamma, PPARG, Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3, NR1C3

Anti-PPAR gamma/PPARG Antibody (2S691) 是一种 Rabbit 抗体,靶向 PPAR gamma/PPARG。Anti-PPAR gamma/PPARG Antibody (2S691) 可用于 WB。

Anti-PPAR gamma/PPARG Antibody (2S691)

Anti-PPAR gamma/PPARG Antibody (2S691)

一键复制产品信息
Rating icon 还可以
货号 TMAC-03397 别名 PPAR-gamma, PPARG, Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3, NR1C3

Anti-PPAR gamma/PPARG Antibody (2S691) 是一种 Rabbit 抗体,靶向 PPAR gamma/PPARG。Anti-PPAR gamma/PPARG Antibody (2S691) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-PPAR gamma/PPARG Antibody (2S691) is a Rabbit antibody targeting PPAR gamma/PPARG. Anti-PPAR gamma/PPARG Antibody (2S691) can be used in WB.
别名PPAR-gamma, PPARG, Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3, NR1C3
Ig Type
IgG
克隆号
2S691
反应种属
Human,Mouse,Rat
验证活性
1. Western blot analysis of PPAR gamma on PC-12 cells lysates using anti-PPAR gamma antibody at 1/1,000 dilution.
verifiedActivity
应用WB
推荐剂量
WB: 1:1000-2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor subfamily of transcription factors. PPARs form heterodimers with retinoid X receptors (RXRs). These heterodimers regulate transcription of genes involved in insulin action, adipocyte differentiation, lipid metabolism and inflammation. PPARγ is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPARγ activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPARγ may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPARγ2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPARγ2 gene maybe correlated with abdominal obesity in type 2 diabetes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 58 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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