购物车
- 全部删除
您的购物车当前为空
Anti-CIB2 Antibody (3T556)
还可以
产品编号 TMAY-02393
别名 USH1J, KIP2, DFNB48, calcium and integrin binding family member 2
Anti-CIB2 Antibody (3T556) 是一种 Rabbit 抗体，靶向 CIB2。Anti-CIB2 Antibody (3T556) 可用于 ELISA,ELISA(Det),IHC-P。
Anti-CIB2 Antibody (3T556)
331 Anti-CIB2 Antibody (3T556)
还可以产品编号 TMAY-02393 别名 USH1J, KIP2, DFNB48, calcium and integrin binding family member 2
Anti-CIB2 Antibody (3T556) 是一种 Rabbit 抗体，靶向 CIB2。Anti-CIB2 Antibody (3T556) 可用于 ELISA,ELISA(Det),IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 795 | 5日内发货 | |
| 100 μL | ¥ 2,289 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CIB2 Antibody (3T556) is a Rabbit antibody targeting CIB2. Anti-CIB2 Antibody (3T556) can be used in ELISA,ELISA(Det),IHC-P. |
| 别名 | USH1J, KIP2, DFNB48, calcium and integrin binding family member 2 |
| Ig Type | Rabbit IgG |
| 克隆号 | 3T556 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human CIB2 in human heart with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CIB2 in human brain with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| 应用 | ELISA,ELISA(Det),IHC-P |
| 推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:1000-1:4000; ELISA(Det): 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CIB2 (rh CIB2; TMPY-02289; O75838; Met 1-Ile 187). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is genetically heterogeneous. The mutations in CIB2, which encodes a calcium- and integrin-binding protein, are associated with nonsyndromic deafness (DFNB48) and Usher syndrome type 1J (USH1J). Furthermore, in zebrafish and Drosophila melanogaster, CIB2 is essential for the function and proper development of hair cells and retinal photoreceptor cells. We also show that CIB2 is a new member of the vertebrate Usher interactome. Variants in CIB2 can underlie either Usher syndrome type I (USH1J) or nonsyndromic hearing impairment (NSHI) (DFNB48). CIB2 is widely expressed in various human and animal tissues, mainly in skeletal muscle, nervous tissue, inner ear, and retina. The CIB2 protein is responsible for maintaining Ca(2+) homeostasis in cells and interacting with integrins-transmembrane receptors essential for cell adhesion, migration, and activation of signaling pathways. Calcium signaling pathway is crucial for signal transduction in the inner ear, and integrins regulate hair cell differentiation and maturation of the stereocilia. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CIB2 protein (TMPY-02289) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
SCI 文献
评论列表
预览
Related Tags: buy Anti-CIB2 Antibody (3T556) | purchase Anti-CIB2 Antibody (3T556) | Anti-CIB2 Antibody (3T556) cost | order Anti-CIB2 Antibody (3T556)
嗨！有任何问题？点我咨询
评论内容