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Anti-FCGRT Antibody (4G656)
还可以产品编号 TMAH-00424
别名 FcRn
Anti-FCGRT Antibody (4G656) 是一种抗体，靶向 FCGRT。Anti-FCGRT Antibody (4G656) 可用于 ELISA, IHC。
Anti-FCGRT Antibody (4G656)
Anti-FCGRT Antibody (4G656)
还可以产品编号 TMAH-00424 别名 FcRn
Anti-FCGRT Antibody (4G656) 是一种抗体，靶向 FCGRT。Anti-FCGRT Antibody (4G656) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-FCGRT Antibody (4G656) is an antibody targeting FCGRT. Anti-FCGRT Antibody (4G656) can be used in ELISA, IHC. |
| 别名 | FcRn |
| Ig Type | hIgG1 |
| 克隆号 | 4G656 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00424 diluted at 1:150 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Endosome membrane. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation. In addition of IgG, regulates homeostasis of the other most abundant circulating protein albumin/ALB. (Microbial infection) Acts as an uncoating receptor for a panel of echoviruses including Echovirus 5, 6, 7, 9, 11, 13, 25 and 29. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human FCGRT Protein |
| 抗原种属 | Human |
| 基因ID | 2217 |
| Uniprot ID | |
| 研究领域 | Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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