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顶部生物活性储存和溶解信息计算器

Anti-JARID2 Antibody (7C209)

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Anti-JARID2 Antibody (7C209)
产品编号 TMAC-02279
别名 Protein Jumonji, Jumonji/ARID domain-containing protein 2, Jumonji/ARID domain containing protein 2, Jumonji protein, Jumonji like protein, Jumonji homolog, Jumonji AT rich interactive domain 2, JMJ, JARID2, JARID 2, JARD2_HUMAN, JARD2

Anti-JARID2 Antibody (7C209) 是一种 Mouse 抗体，靶向 JARID2。Anti-JARID2 Antibody (7C209) 可用于 WB,ICC,FCM。

Anti-JARID2 Antibody (7C209)

Anti-JARID2 Antibody (7C209)

Rating icon 还可以
Anti-JARID2 Antibody (7C209)
产品编号 TMAC-02279 别名 Protein Jumonji, Jumonji/ARID domain-containing protein 2, Jumonji/ARID domain containing protein 2, Jumonji protein, Jumonji like protein, Jumonji homolog, Jumonji AT rich interactive domain 2, JMJ, JARID2, JARID 2, JARD2_HUMAN, JARD2

Anti-JARID2 Antibody (7C209) 是一种 Mouse 抗体，靶向 JARID2。Anti-JARID2 Antibody (7C209) 可用于 WB,ICC,FCM。

规格价格库存数量
50 μL
¥ 1,995
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-JARID2 Antibody (7C209) is a Mouse antibody targeting JARID2. Anti-JARID2 Antibody (7C209) can be used in WB,ICC,FCM.
别名Protein Jumonji, Jumonji/ARID domain-containing protein 2, Jumonji/ARID domain containing protein 2, Jumonji protein, Jumonji like protein, Jumonji homolog, Jumonji AT rich interactive domain 2, JMJ, JARID2, JARID 2, JARD2_HUMAN, JARD2
交叉反应
Human
验证活性
1. Western blot analysis of JARID2 on human JARID2 recombinant protein using anti-JARID2 antibody at 1/1,000 dilution.
2. Western blot analysis of JARID2 on HEK293 (1) and JARID2-hIgGFc transfected HEK293 (2) cell lysate using anti-JARID2 antibody at 1/1,000 dilution.
3. ICC staining JARID2 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Hela cells with JARID2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
WB
ICC
FCM
推荐剂量
WB: 1:500-2000; ICC: 1:50-200; FCM: 1:100-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q92833
化学信息
分子量Theoretical: 139 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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