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Anti-IGFBP-6 Antibody (1Y17)

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Anti-IGFBP-6 Antibody (1Y17)
产品编号 TMAY-03305
别名 insulin-like growth factor binding protein 6

Anti-IGFBP-6 Antibody (1Y17) 是一种 Rabbit 抗体,靶向 IGFBP-6。Anti-IGFBP-6 Antibody (1Y17) 可用于 ELISA,IHC-P。

Anti-IGFBP-6 Antibody (1Y17)
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Anti-IGFBP-6 Antibody (1Y17)

Rating icon 还可以
Anti-IGFBP-6 Antibody (1Y17)
产品编号 TMAY-03305 别名 insulin-like growth factor binding protein 6

Anti-IGFBP-6 Antibody (1Y17) 是一种 Rabbit 抗体,靶向 IGFBP-6。Anti-IGFBP-6 Antibody (1Y17) 可用于 ELISA,IHC-P。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-IGFBP-6 Antibody (1Y17) is a Rabbit antibody targeting IGFBP-6. Anti-IGFBP-6 Antibody (1Y17) can be used in ELISA,IHC-P.
别名insulin-like growth factor binding protein 6
Ig Type
Rabbit IgG
克隆号
1Y17
交叉反应
Mouse
验证活性
Immunochemical staining of mouse IGFBP6 in mouse skeletal muscle with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用
ELISA,IHC-P
推荐剂量
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IGFBP6 / IBP6 (rM IGFBP6 / IBP6; TMPY-02118; NP_032370.2; Met1-Gly238).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in 20 mM MES, 100 mM NaCl, 10% Trehalose, pH 6.0
研究背景Insulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGF-binding protein-4 (IGFBP-4) inhibits IGF-I action in vitro and is the most abundant IGFBP in the rodent arterial wall. IGFBP6 is directly downregulated by the beta-catenin/TCF complex in desmoid tumors, and imply a role for the IGF axis in the proliferation of desmoid tumors. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse IGFBP6 / IBP6 Protein (TMPY-02118)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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