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Anti-BOLA1 Antibody (2Q815) 是一种 Rabbit 抗体,靶向 BOLA1。Anti-BOLA1 Antibody (2Q815) 可用于 ELISA。
Anti-BOLA1 Antibody (2Q815) 是一种 Rabbit 抗体,靶向 BOLA1。Anti-BOLA1 Antibody (2Q815) 可用于 ELISA。
产品描述 | Anti-BOLA1 Antibody (2Q815) is a Rabbit antibody targeting BOLA1. Anti-BOLA1 Antibody (2Q815) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2Q815 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human BOLA1/hBolA (rh BOLA1/hBolA; TMPY-04022; Q9Y3E2; Met1-Pro137). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | BOLA1 is a mitochondrial protein that counterbalances the effect of L-buthionine-(S,R)-sulfoximine (BSO)-induced glutathione (GSH) depletion on the mitochondrial thiol redox potential. Furthermore, overexpression of BOLA1 nullifies the effect of BSO and S-nitrosocysteine on mitochondrial morphology. Conversely, knockdown of the BOLA1 gene increases the oxidation of mitochondrial thiol groups. Supporting a role of BOLA1 in controlling the mitochondrial thiol redox potential is that BOLA1 orthologs only occur in aerobic eukaryotes. A measured interaction of BOLA1with the mitochondrial monothiol glutaredoxin GLRX5 provides hints for potential mechanisms behind BOLA1's effect on mitochondrial redox potential. |
偶联 | Unconjugated |
免疫原 | Recombinant Human BOLA1/hBolA Protein (TMPY-04022) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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