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顶部生物活性储存和溶解信息计算器

Anti-DAXX Antibody (9O762)

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产品编号 TMAC-01118

别名 MGC126246, MGC126245, hDaxx, Fas death domain associated protein, Fas binding protein, ETS1 associated protein 1, EAP1, EAP 1, Death domain associated protein 6, Death associated protein 6, DAP6, DAP 6, CENP-C binding protein, BING2, BING 2

Anti-DAXX Antibody (9O762) 是一种 Rabbit 抗体，靶向 DAXX。Anti-DAXX Antibody (9O762) 可用于 FCM,ICC,WB。

Anti-DAXX Antibody (9O762)

Anti-DAXX Antibody (9O762)

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Rating icon 还可以
产品编号 TMAC-01118 别名 MGC126246, MGC126245, hDaxx, Fas death domain associated protein, Fas binding protein, ETS1 associated protein 1, EAP1, EAP 1, Death domain associated protein 6, Death associated protein 6, DAP6, DAP 6, CENP-C binding protein, BING2, BING 2

Anti-DAXX Antibody (9O762) 是一种 Rabbit 抗体，靶向 DAXX。Anti-DAXX Antibody (9O762) 可用于 FCM,ICC,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-DAXX Antibody (9O762) is a Rabbit antibody targeting DAXX. Anti-DAXX Antibody (9O762) can be used in FCM,ICC,WB.
别名MGC126246, MGC126245, hDaxx, Fas death domain associated protein, Fas binding protein, ETS1 associated protein 1, EAP1, EAP 1, Death domain associated protein 6, Death associated protein 6, DAP6, DAP 6, CENP-C binding protein, BING2, BING 2
Ig Type
IgG
克隆号
9O762
交叉反应
Human
验证活性
1. Western blot analysis of Daxx on different lysates using anti-Daxx antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: A549, Lane 3: SW480.
2. ICC staining Daxx in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Daxx in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Hela cells with Daxx antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用FCMICCWB
推荐剂量
WB: 1:1000-2000; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Activation of the cell surface receptor FAS by FAS ligand leads to the initiation of apoptosis, a process necessary for the regulation of the immune system and tissue homeostasis. FAS-mediated apoptosis appears to involve a number of divergent and overlapping pathways. Daxx appears to be a central component of a FAS-mediated apoptotic pathway involving the activation of Jun N-terminal kinase (JNK). Although Daxx itself does not contain a death domain, it specifically binds to the death domain of FAS. Overexpression of Daxx activates the JNK pathway and enhances FAS-mediated apoptosis. The Daxx apoptotic pathway acts cooperatively with but is distinct from the FAS-mediated pathway that involves interactions between the death domain-containing protein FADD and the cysteine protease FLICE. Unlike the FAS-FADD-FLICE pathway, the Daxx pathway is sensitive to the apoptotic inhibitor protein Bcl-2.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q9UER7
化学信息
分子量Theoretical: 81 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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