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Anti-JAM-A Antibody-FITC (5E755)

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产品编号 TMAY-00440F

Anti-JAM-A Antibody-FITC (5E755) 是一种 FITC-conjugated Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody-FITC (5E755) 可用于 FCM。

Anti-JAM-A Antibody-FITC (5E755)

Anti-JAM-A Antibody-FITC (5E755)

Rating icon 还可以
产品编号 TMAY-00440F

Anti-JAM-A Antibody-FITC (5E755) 是一种 FITC-conjugated Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody-FITC (5E755) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-JAM-A Antibody-FITC (5E755) is a FITC-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-FITC (5E755) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
克隆号
5E755
交叉反应
Human
验证活性
Profile of anti-JAM-A (CD321) reactivity on SKBR3 cells analyzed by flow cytometry.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAM-A / F11R / CD321 (rh JAM-A / F11R / CD321; TMPY-01035; NP_058642.1; Met 1-Ala 242) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Human JAM-A / F11R / CD321 protein (TMPY-01035)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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