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Anti-JAM-A Antibody-FITC (5E755) 是一种 FITC-conjugated Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody-FITC (5E755) 可用于 FCM。
Anti-JAM-A Antibody-FITC (5E755) 是一种 FITC-conjugated Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody-FITC (5E755) 可用于 FCM。
产品描述 | Anti-JAM-A Antibody-FITC (5E755) is a FITC-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-FITC (5E755) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 5E755 |
交叉反应 | Human |
验证活性 | Profile of anti-JAM-A (CD321) reactivity on SKBR3 cells analyzed by flow cytometry. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAM-A / F11R / CD321 (rh JAM-A / F11R / CD321; TMPY-01035; NP_058642.1; Met 1-Ala 242) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/APC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human JAM-A / F11R / CD321 protein (TMPY-01035) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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