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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody

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货号 TMAB-10899

Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-KSR1 (Ser404)。Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody 可用于 WB。

Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody

Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10899

Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-KSR1 (Ser404)。Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody is a Rabbit antibody targeting Phospho-KSR1 (Ser404). Anti-Phospho-KSR1 (Ser404) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景KSR1 is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. It was initially considered to be a protein kinase acting in the Ras pathway. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane associated.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human KSR1 around the phosphorylation site of Ser404
抗原种属
Human
基因名称
KSR1
基因ID
8844
蛋白名称
Kinase suppressor of Ras 1
Uniprot ID
Q8IVT5
功能
Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.
化学信息
分子量Theoretical: 102 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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