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Anti-Laminin alpha 4 Polyclonal Antibody

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货号 TMAB-08207

Anti-Laminin alpha 4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Laminin alpha 4。Anti-Laminin alpha 4 Polyclonal Antibody 可用于 ICC/IF。

Anti-Laminin alpha 4 Polyclonal Antibody

Anti-Laminin alpha 4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08207

Anti-Laminin alpha 4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Laminin alpha 4。Anti-Laminin alpha 4 Polyclonal Antibody 可用于 ICC/IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Laminin alpha 4 Polyclonal Antibody is a Rabbit antibody targeting Laminin alpha 4. Anti-Laminin alpha 4 Polyclonal Antibody can be used in ICC/IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep)
应用ICC/IF
推荐剂量
ICC/IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted; extracellular space; extracellular matrix; basement membrane. Major component.
组织特异性In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver; weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Laminins are essential and abundant structural non-collagenous glyco- proteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing Type IV collagen networks, Nidogen, and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of a, b, and g chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human Laminin a-4 gene maps to chromosome 6q21 and is expressed in adult heart, lung, ovary, small and large intestines, liver, and placenta.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Laminin alpha 4
抗原种属
Human
基因名称
LAMA4
基因ID
3910
蛋白名称
Laminin subunit alpha-4
Uniprot ID
Q16363
功能
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
化学信息
分子量Theoretical: 200 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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