您的购物车当前为空
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 489 | 20日内发货 | |
| 10 μg | ¥ 797 | 20日内发货 | |
| 20 μg | ¥ 1,320 | 20日内发货 | |
| 50 μg | ¥ 1,970 | 20日内发货 | |
| 100 μg | ¥ 2,680 | 20日内发货 | |
| 200 μg | ¥ 4,160 | 20日内发货 | |
| 500 μg | ¥ 7,490 | 20日内发货 | |
| 1 mg | ¥ 11,700 | 20日内发货 |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 产品描述 | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-6xHis-SUMO |
| 蛋白编号 | Q9BV47 |
| 别名 | SKRP3,Novel amplified gene in thyroid anaplastic cancer,NATA1,MKP8,Mitogen-activated protein kinase phosphatase 8 (MAP kinase phosphatase 8;MKP-8),Low-molecular-mass dual-specificity phosphatase 4 (DSP-4;LDP-4),LDP4,DUSP26,DUSP24,Dual specificity protein phosphatase 26,Dual specificity phosphatase SKRP3 |
| 氨基酸序列 | MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLEA |
| 蛋白构建 | 1-211 aa |
| 蛋白纯度 | > 90% as determined by SDS-PAGE. |
| 分子量 | 39.9 kDa (predicted) |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 缓冲液 | Tris-based buffer, 50% glycerol |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |